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46 Interestingly, in the BIG 1 98 trial a randomized, double blind, phase III study that showed letrozole improved DFS compared to tamoxifen for postmenopausal women with hormone receptor positive disease 47, 48 the investigators found a greater benefit from letrozole compared to tamoxifen in tumors with a higher Ki67 labeling index lasix 20 mg Estimated glomerular filtration rate eGFR slope is analyzed based on the treated set considering measurements until end of treatment
46 Interestingly, in the BIG 1 98 trial a randomized, double blind, phase III study that showed letrozole improved DFS compared to tamoxifen for postmenopausal women with hormone receptor positive disease 47, 48 the investigators found a greater benefit from letrozole compared to tamoxifen in tumors with a higher Ki67 labeling index lasix 20 mg Estimated glomerular filtration rate eGFR slope is analyzed based on the treated set considering measurements until end of treatment